面向医学治疗的微纳米技术
2008-5
科学出版社
（加）德塞（Desai，T.）（美）马蒂亚（Bhatia，S.） 编著，Therapeutic Micro/Nano Technology.-影印本
372
470000
本书讨论了正在兴起的治疗性微米和纳米技术领域。本书所覆盖的主题包括：基于细胞的治疗技术，再生医学——细胞与微米和纳米系统整合（融合），MEMS与细胞和组织的集成；药物的传递-用于血管内物靶向传递的纳米粒子和非血管系统的药物传递系统（植入性的、口服的、吸入性的）；用于生物界面的分子表面工程，生物分子图案化和细胞图案化。 本书可供从事纳米科技、材料科学、生物化学和医学的科研人员，高等院校研究生、教学人员参考。
作者：(加拿大)德塞(Desai T．) (美国)巴蒂亚( Bhatia S)
List of ContributorsForewordPrefaceI.Cell-based Therapeutics 1.Nano-and Micro-Technology to Spatially and Temporally Control Proteins for Neural Regeneration Anjana Jain and Ravi V Bellamkonda 1.1 Introduction 1.1.1 Response after Injury in CNS and PNS 1.1.2 Nano-and Micro-scale Strategies to Promote Axonal Outgrowth in the CNS and PNS 1.2 Spatially Controlling Proteins 1.2.1 Spatial Control: Permissive Bioactive Hydrogel Scaffolds for Enhanced Regeneration 1.2.2 Spatial Control: Chemical vs.Photochemical Crosslinkers for Immobilization of Bioactive Agents 1.2.3 Other Hydrogel Scaffolds 1.2.4 Spatial Control: Contact.Guidance as a Strategy to Promote Regeneration 1.2.5 Spatial Control: Nerve Guide Conduits Provide an Environment for Axonal Regeneration 1.2.6 Spatial Control: Cell-scaffold Constructs as a Way of Combining Permissive Substrates with Stimuli for Regeneration 1.3 Temporally Controlling the Release of Proteins 1.3.1 Temporal Control: Osmotic Pumps Release Protein to Encourage Axonal Outgrowth 1.3.2 Temporal Control: Slow Release of Trophic Factors Using Microspheres 1.3.3 Temporal Control: Lipid Microtubules for Sustained Release of Stimulatory Trophic Factors 1.3.4 Temporal Control: Demand Driven Release of Trophic Factors 1.4 Conclusion References 2.3-D Fabrication Technology for Tissue Engineering Alice A.Chen, Valerie Liu Tsang, Dirk Albrecht, and Sangeeta N.Bhatia 2.1 Introduction 2.2 Fabrication of Acellular Constructs 2.2.1 Heat-Mediated 3D Fabrication 2.2.2 Light-Mediated Fabrication 2.2.3 Adhesive-Mediated Fabrication 2.2.4 Indirect Fabrication by Molding 2.3 Fabrication of Cellular Constructs 2.4 Fabrication of Hybrid Cell/Scaffold Constructs 2.4.1 Cell-laden Hydrogel Scaffolds by Molding 3.3.4 Extensive Neurite Outgrowth and Active Synapse Formation on PuraMatrix 3.3.5 Compatible with Bioproduction and Clinical Application 3.3.6 Synthetic Origin and Clinical-Grade Quality 3.3.7 Tailor-Made PuraMatrix 3.4 Peptide Surfactants/Detergents Stabilize Membrane Proteins 3.5 Perspective and Remarks Acknowledgements References 4.At the Interface: Advanced Mierofluidic Assays for Study of Cell Function Yoko Kamotani, Dongeun Huh, Nobuyuki Futai, and Shuichi Takayama 4.1 Introduction 4.2 Microfabrication 4.2.1 Soft Lithography …… 5.Multi-phenotypie Cellular Arrays for Biosensing 6.MEMS and NeurosurgeryII.Drug Delivery 7.Vascular Zip Codes and Nanoparticle Targeting 8.Engineering Biocompatible Quantum Dots for Ultrasensitive,Real-Time Biological Imaging and Detection 9.Diagnostic and Therapeutic Applications of Metal Nanoshells 10.Nanoporous Microsystems for Islet Cell Replacement 11.Medical Nanotechnology and Pulmonary Pathology 12.Nanodesigned Pore-Containing Systems for Biosensing and Controlled Drug Release 13.Trandermal Drug Delivery using Low-Frequency Sonophoresis 14.Microdevices for Oral Drug Delivery 15.Nanoporous Implants for Controlled Drug DeliveryIII.Molecular Surface Engineering for the Biological Interface 16.Micro and Nanoscale Smart Polymer Technologies in Biomedicine 17.Supported Lipid Bilayers as Mimics for Cell Surfaces 18.Engineering Cell Adhesion 19.Cell Biology on a ChipAbout the EditorsIndex
《面向医学治疗的微纳米技术(影印版)》由科学出版社出版。
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