凯利风湿病学
2002-8
人民卫生出版社
路迪
1788
5234000
More than 20 years ago, in the preface to the first edition of the Textbook of Rheumatology, we suggested that "The field of rheumatology has come of age." What we meant was that rheumatology had shed its strictly empirical base and its host of unproven remedies and become a healing discipline thoroughly grounded in science. We thought it was time for a new textbook, one that reflected this passage through epistemological puberty. The sixth edition reflects the maturation of rheumatology as a subspecialty. It is instructive to compare the contents of the first and sixth editions. Many chapters have disappeared entirely, and their material has been condensed and incorporated into existing chapters. Consider, for example, that in the basic science section of the first edition we devoted entire chapters to immunoglobulin structure, the contact activation system, and lysosomes (not to mention purine metabolism, a subject dear to the heart of the then senior editor). Cyclic nucleotides and eosinophilic chemotactic factor of anaphylaxis figured prominently in the titles of other basic science chapters. None of these has a place in the Table of Contents of the current edition. Instead, there are chapters dealing with dendritic cells, leukotrienes, mast cells, nitric oxide, fibroblasts, cytokines, and apoptosis. The importance of these topics to understanding the rheumatic diseases was unknown 20 years ago, and some of them hadn't even been discovered! Who can imagine what the scientific basis of rheumatology will be in the 10th edition, 20 years from now? Surely, knowledge obtained from the working through of the human genome will figure prominently.
VOLUME 1 Section 1 BIOLOGY OF THE NORMAL JOINT 1. BIOLOGY OF THE NORMAL JOINT 2. COLLAGEN AND ELASTIN 3. MATRIX GLYCOPROTEINS,PROTEOGLYCANS,AND CARTILAGE 4. PROTEINASES AND MATRIX DEGRADATION 5. BIOMECHANICS OF JOINTS Section 2 IMMUNE AND INFLAMMATORY RESPONSES 6. MACROPHAGES,DENDRITIC CELLS,AND FOLLICULAR DENDRITIC CELLS 7. GENETICS OF RHEUMATIC DISEASES 8. T LYMPHOCYTES 9. B CELLS 10. RHEUMATOID FACTOR 11. ANTINUCLEAR ANTIBODIES 12. IMMUNE COMPLEXES 13. COMPLEMENT 14. NEUTROPHILS AND EOSINOPHILS 15. PROSTAGLANDINS,LEUKOTRIENES,AND RELATED COMPOUNDS 16. THE MAST CELL 17. ENDOTHELIAL CELLS AND NITRIC OXIDE 18. PLATELETS 19. FIBROBLAST FUNCTION AND FIBROSIS 20. CYTOKINES 21. APOPTOSIS 22. AUTOMMUNITY Section 3 EVALUATION OF THE PATIENT 23. EPIDEMIOLOGY OF THE RHEUMATIC DISEASES 24. EVIDENCE-BASED RHEUMATOLOGY 25. EXAMINATION OF THE JOINTS 26. MONARTICULAR ARTHRITIS 27. POLYARTICULAR ARTHRITIS 28. WEAKNESS 29. THE EYE AND RHEUMATIC DISEASE 30. THE SKIN Section 4 MUSCULOSKELETAL PAIN AND EVALUATION 31. FIBROMYALGIA 32. OCCUPATIONAL AND RECREATIONAL MUSCULOSKELETAL DISORDERS 33. SPORTS MEDICINE 34. NECK PAIN 35. SHOULDER PAIN 36. LOW BACK PAIN 37. HIP AND KNEE PAIN 38. ANKLE AND FOOT PAIN 39. TEMPOROMANDIBULAR JOINT PAIN 40. HAND AND WRIST PAIN Section 5 DIAGNOSTIC TESTS AND PROCEDURES 41. ASPIRATION AND INJECTION OF JOINTS AND SOFT TISSUES 42. SYNOVIAL FLUID ANALYSIS AND SYNOVIAL BIOPSY 43. IMAGING 44. ARTHROSCOPY AND SYNOVECTOMY 45. LABORATORY EVALUATION OF INFLAMMATION 46. BIOLOGIC MARKERS Section 6 SPECIAL ISSUES 47. NUTRITION AND RHEUMATIC DISEASES 48. PSYCHOSOCIAL MANAGEMENT OF RHEUMATIC DISEASES 49. GERIATRICS AND THE RHEUMATIC DISEASES 50. ALTERNATIVE CARE FOR ARTHRITIS AND RELATED MUSCULOSKELETAL DISEASES 51. CHRONIC PAIN MANAGEMENT 52. REHABILITATION OF PATIENTS WITH RHEUMATIC DISEASES 53. HEALTH OUTCOME ASSESSMENT Section 7 CLINICAL PHARMACOLOGY 54. DEVELOPING A CLINICAL TRIAL DESIGN 55. NONSTEROIDAL ANTI-INFLAMMATORY DRUGS 56. GLUCOCORTICOIDS 57. METHOTREXATE 58. SULFASALAZINE 59. ANTIMALARIAL DRUGS 60. GOLD AND PENICILLAMINE 61. IMMUNOREGULATORY DRUGS 62. BIOLOGIC AGENTS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS 63. TETRACYCLINES INDEXVOLUME 2 Section 8 RHEUMATOID ARTHRITIS Section 9 SPONDYLOARTHROPATHIES Section 10 SYSTEMIC LUPUS ERYTHEMATOSUS AND RELATED SYNDROMES Section 11 VASCULITIC SYNDROMES Section 12 SCLERODERMA AND MIXED CONNECTIVE TISSUE DISEASES Section 13 STRUCTURE,FUNCTION,AND DISEASE OF MUSCLE Section 14 RHEUMATIC DISEASES OF CHILDHOOD Section 15 CRYSTAL-ASSOCIATED SYNOVITIS Section 16 OSTEOARTHRITIS,POLYCHONDRITIS,AND HERITABLE DISORDERS Section 17 ARTHRITIS RELATED TO INFECTION Section 18 ARTHRITIS ACCOMPANYING SYSTEMIC DISORDERS Section 19 DISORDERS OF BONE AND STRUCTURAL PROTEIN Section 20 TUMORS INVOLVING JOINTS Section 21 RECONSTRUCTIVE SURGERY FOR RHEUMATIC DISEASE INDEX
