有机合成中的现代方法
2004-11
世界图书出版公司
W.Carruthers
526
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有机合成中的现代方法，ISBN：9787506272506，作者：（ ）W.Carruthers著
Preface to the first editionPreface to the third edition1 Formation of carbon-carbon single bonds 1.1. Alkylation: importance of enolate anions 1.2. Alkylation of relatively acidic methylene groups 1.3. y-Alkylation of 1,3-dicarbonyl compounds; dianions in synthesis 1.4. Alkylation of ketones 1.5. The enamine and related reactions 1.6. Alkylation of a-thio and a-seleno carbanions 1.7. Umpolung (dipole inversion) 1.8. The aldol reaction 1.9. Allylic alkylation of alkenes 1.10. The dihydro-l,3-oxazine synthesis of aldehydes and ketones 1.11. Coupling of organonickel and organocopper com- plexes 1.12. Reactions of lithium organocuprates: copper-cata-lysed reactions of Grignard reagents 1.13. Synthetic applications of carbenes and carbenoids 1.14. Formation of carbon-carbon bonds by addition of free radicals to alkenes 1.15. Some photocyclisation reactions2 Formation of carbon--carbon double bonds 2.1. β-Elimination reactions 2.2. Pyrolytic syn eliminations 2.3. Sulphoxide-sulphenate rearrangement; synthesis of allyl alcohols 2.4. The Wittig and related reactions 2.5. Alkenes from sulphones 2.6. Decarboxylation of β-lactones 2.7. Stereoselective synthesis of tri- and tetra- substituted alkenes 2.8. Fragmentation reactions 2.9. Oxidative decarboxylation of carboxylic acids 2.10. Alkenes from arylsuiphonylhydrazones 2.11. Stereospecific synthesis from 1,2-diols 2.12. Claisen rearrangement of allyl vinyl ethers 2.13. Reductive dimerisation of carbonyl compounds3 The Diels-Alder and related reactions 3.1. General 3.2. The dienophile - heterodienophiles, oxygen as a dienophile 3.3. The diene - acyclic dienes, heterodienes, 1,2-dimethylenecycloalkanes, vinylcycloalkenes and vinylarenes, aromatic hydrocarbons, cyclic dienes, cyclopentadienones and ortho-quinones, furans 3.4. Intramolecular Diels-Alder reactions 3.5. The retro Diels-Alder reaction 3.6. Catalysis by Lewis acids 3.7. Regiochemistry of the Diels-AIder reaction 3.8. "Stereochemistry of the Diels-Alder reaction 3.9. Asymmetric Diels-Alder reactions 3.10. Mechanism of the Diels-Aider reaction 3.11. Photosensitised Diels-Alder reactions 3.12. The erie reaction 3.13. Cyclo-addition reactions with allyl cations and allyl anions 3.14. 1,3-Dipolar cyclo-addition reactions4 Reactions at uaactivated C--H bonds 4.1. The Hoffmann-Loeffler-Freytag reaction 4.2. Cyclisation reactions of nitrenes 4.3. The Barton reaction and related processes - photoly-sis of organic nitrites and hypohalites, photolysis of N-nitrosoamides 4.4. Reaction of monohydric alcohols with lead tetra-acetate 4.5. Miscellaneous reactions - unsaturated alcohols from hydroperoxides, cyclobutanols by photolysis of ketones, long-range functionalisation of unacti-vated carbons on the steroid nucleus5 Cynthetic applications of organoboranes and organosilanes6 Oxidation7 ReductionReferencesIndex
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