vander肾脏生理学 Vander＇s Renal Physiology

2002-2  

McGraw-Hill Medical  

Douglas Eaton  

214  

This concise overview of renal physiology introduces basic science principles and their relevance in the clinical expression of disease. Each chapter incorporates a wealth of pedagogical aids including: study questions, learning objectives, and clinical examples. Also serves as a good review for the USMLE Step 1. 　　作者简介：　　Douglas C. Eaton, Ph.D.: Distinguished Professor, Department of Physiology; and Director, Center for Cell and Molecular Signaling, Emory University Medical School, Atlanta John Pooler, Ph.D.: Associate Professor of Physiology, Department of Physiology, Emory University Medical School, Atlanta .

PrefaceChapter 1 Renal Functions,Snatomy,and Basic Processes　Functions　Anatomy of the Kidneys and Urinary System　The Nephron　Blood Supply to the Nephrons　Basic Renal ProcessesChapter 2 Renal Blood Flow and Glomerular Filtration　Glomerular Filtration and Renal Blood Flow　Flow, Resistance, and Pressure in The Kidneys　Glomerular Filtration　AutoregulationChapter 3 Clearance　Clearance Units　Plasma Creatinine and Urea Concentrations as Indicators of GFR ChangesChapter 4 Basic Transport Mechanisms　Crossing the Epithelial Barriers　Receptor-Mediated Endocytosis and Transcytosis　Transport Mechanisms in ReabsorptionChapter 5 Renal Handling of Organic Substances　Active Proximal Reabsorption of Organic Nutrients (Eg, Glucose, Amino Acids)　Proteins and Peptides　Active Proximal Secretion of Organic Anions　Active Proximal Secretion of Organic Cations　pH Dependence of Passive Reabsorption or Secretion UreaChapter 6 Basic Renal Processes for Sodiun,Chloride,and Water　Overview　Individual Tubular Segments　Urinary Concentration: The Medullary Osmotic GradientChapter 7 Control of Sodium and Water Excretion:Regulation of Plasma Volume and Plasma Osmolality and Renal Control of Systemic Blood Pressure　Regulation of Blood Pressure　Contribution of The Kidney to The Long-Term Regulation of Blood Pressure 　Control of Sodium Balance　Control of Water ExcretionChapter 8 Renal Regulation of Potassium Balance　Regulation of Potassium Between the Intracellular and Extracellular Compartments　Renal Potassium HandlingChapter 9 Regulation of Hydrogen Ion balance　Guidelines for Studying Acid-Base Biology　Renal Handling of Acids and Bases　Renal Excretion of Acid and Base　Hydrogen Ion Excretion on Urinary Buffers　Phosphate and Organic Acids as Buffers　Hydrogen Ion Excretion on Ammonium　Quantification of Renal Acid-Base Excretion　Regulation of the Renal Handling of Acids and Bases　Control of Renal Glutamine Metabolism and NH4 Excretion　Intravenous Solutions: Lactated Ringer's　Specific Categories of Acid-Base Disorders　Renal Response to Metabolic Acidosis and Alkalosis　Factors Causing the Kidneys to Generate or Maintain　A Metabolic AlkalosisChapter 10 Regulation of Calcium and phosphate Balance　Effector Sites for Calcium Balance　Hormonal Control of Effector Sites　Overview of Renal Phosphate HandlingAnswers to Study Questions Appendix AAppendix BIndex

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