Innate Immunity to Pulmonary Infection - No. 279肺感染先天性免疫

2007-1  

John Wiley & Sons Inc  

Novartis Foundation  

228  

　　Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. 　　Innate Immunity to Pulmonary Infection: 　　Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung 　　Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases 　　Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage 　　Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors 　　Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention ？（vaccination） strategies 　　Includes contributions from an international and interdisciplinary group of experts 　　Innate Immunity to Pulmonary Infection is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.

Symposium on Innate immunity to pulmonary infection, held at the Wolfson Pavillion,University of Cape Town Medical School, South Africa, 28-30 November 2005Editors: Derek J. Chadwick (Organizer) and]amie GoodeThis symposium is based on a proposal made by Siamon Gordon and Gordon BrownSiamon Gordon Chair's introductionEric D. Bateman and Anamika Jithoo Lung diseases in South Africa: an overview DiscussionPaul D. van Helden, Marlo Mo11er, Chantal Babb, Robin Warren, Gerhard Walzl, Pieter Uys and Eileen Hoal TB epidemiology and human genetics DiscussionDavid P. Speert Bacterial infections of the lung in normal and immunodeficient patients DiscussionMalik Peiris Pathogenesis of avian flu H5N1 and SARS DiscussionClaudia Montagnoli, Silvia Bozza, Roberta Gaziano, Teresa Zelante, Pierluigi Bonifazi, Silvia Moretti, Silvia Bellocchio, Lucia Pitzurra and Luigina Romani Immunity and tolerance to Aspergillusfumigatus DiscussionCecilia Garlanda, Barbara Bottazzi, Giovanni Salvatori, Rita De Santis,Alessia Cotena, Livija Deban, Viriginia Maina, Federica Moalli, Andrea Doni, Tania Veliz-Rodriguez and Alberto Mantovani Pentraxins in innate immunity and inflammation DiscussionAnthony W. Segal How superoxide production by neutrophil leukocytes kills microbes DiscussionRalph M. Steinman Linking innate to adaptive immunity through dendritic cells DiscussionGordon D. Brown Macrophage receptors and innate immunity: insights from dectin-1 DiscussionBernhard Ryffel, Muazzam Jacobs, Shreemanta Parida, Tania Botha,Dieudonnee Togbe and Valerie Quesniaux Toll-like receptors and control of mycobacterial infection in mice DiscussionT. J. Williams and C. t. Weller Population of lungs by mast cells DiscussionJohn K. Sheehan, Mehmet Kesimer and Raymond Pickles Innate immunity and mucus structure and function DiscussionR. B. Sire, H. Clark, K. Hajela and K. R. Mayilyan Collectins and host defence DiscussionBart N. Lambrecht and Leonie S. van Rijt Infections and asthma pathogenesis: a critical role for dendritic cells? Discussiont. A. Vella and O. J. Finn Innate and adaptive immunity in lung cancer DiscussionSiamon Gordon Summing-up Index of contributors Subject index

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