神经胶质细胞
2010-8
科学出版社
斯奎尔 编
544
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《神经科学百科全书》原书篇幅巨大，为所有神经科学百科全书之首。由来自世界各地的2400多位专家撰稿人合力打造，覆盖了神经科学全部主要领域。每个词条在收入书中之前均经过顾问委员会的同行评议，词条中均含有词汇表、引言、参考文献和丰富的交叉参考内容。 主编为著名神经科学家、美国神经科学学会前主席LarryR.Squire。内容平易，本科生即可读懂。深度和广度独一无二，足可满足专家学者的需要。导读版精选原书中的部分主题，按内容重新编排，更适合国内读者购买和阅读。
编者：（美国）斯奎尔（Larry R.Squire）
神经胶质细胞：起源、多样性与功能 Activity-Dependent Metabolism in Glia and Neurons Astrocyte: Calcium Signaling Astrocyte: Identification Methods Astrocyte: Neurotransmitter and Hormone Receptors Astrocyte: Response to Injury Axon Guidance by Glia Axonal Regeneration: Role of the Extracellular Matrix and the Glial Scar Bergmann Glial Cells Calcium Homeostasis in Glia Calcium Waves in Glia Cytokine Receptors in Glia Enteric Nervous System: Glial Cells and Interstitial Cells of Cajal Ependymal Cells Gap Junctions and Hemichannels in Glia Glia and Stroke Glia Control of Blood Flow Glial Cells: Astrocytes and Oligodendrocytes during Normal Brain Aging. Glial Cells: Invertebrate Glial Cells: Microglia during Normal Brain Aging Glial Cells: T Cell Interactions Glial Energy Metabolism: A NMR Spectroscopy Perspective Glial Energy Metabolism: Overview Glial Glutamate and GABA Metabolism Glial Glutamate Transporters Glial Glutamate Transporters: Electrophysiology Glial Glycogen Metabolism Glial Growth Factors Glial Influence on Synaptic Transmission Glial Ion Homeostasis: A Fluorescence Microscopy Approach Glial Plasticity and Neuroendocrine Regulation Glial Responses to Injury Glial Responses to Virus Infection Giial Steroid Metabolism Glioma Intermediate Filaments Ionic Channels in Glia Macroglial Lineages Microglia Identification Methods Microglia Properties Microglial Response to Injury Myelin: Molecular Architecture of CNS and PNS Myelin Sheath Neuron-Glia pH Regulation Neuron-Glia Coupling in Glutathione Metabolism Neuropeptides and Receptors in Glia Neurotransmitter and Hormone Receptors on Oligodendrocytes and Schwann Cells Neurotransmitter Release from Astrocytes Oligodendrocyte and Schwann Cell Identification Methods Oligodendrocyte Morphology Oligodendrocyte Specification Potassium Homeostasis in Glia Radial Glial Cells: Brain Functions Retinal Glia Schwann Cell Development Schwann Cell Morphology Schwann Cells and Axon Relationship Schwann Cells and Plasticity of the Neuromuscular Junction Transplantation of Myelin Forming Cells Transporter Proteins in Neurons and Glia能量与离子的细胞内调控 Activity-Dependent Regulation of Glucose Transporters Brain Glucose Metabolism:Age, Alzheimer's Disease, and ApoE Allele Effects Brain Injury: Magnetic Resonance Studies of Metabolic Aspects Brain Na,K-ATPase Cell-Cell Communication Through the Extracellular Space Intracellular Calcium and Neuronal Death Mitochondrial Dysfunction in Nervous System Injury Monocarboxylate Transporters Regulation of Cell Volume in Neural Cells原书词条中英对照表
插图：Approximately 10 years ago, transgenic mice weregenerated in which the green fluorescent proteinsS65T-GFP or later EGFP were used to label astro-cytes. The unique advantage of fluorescent proteinsis buried in their structure, in which the fluorophor isspontaneously generated from three residues of thepolypeptide chain （by cyclization and oxidation）. Noexogenous cofactors are needed as labeling dyes.GFAP-GFP transgenic mice revolutionized the identi-fication of astrocytes in brain tissue. For the first time,it was possible to unequivocally identify astrocytes inall brain regions without prior immunohistochemicallabeling, which normally requires tissue fixation. Liveastrocytes could be analyzed in acutely isolated brainslices or even in vivo. Via fluorescence-activatedcell sorting, fluorescent astrocytes could be isolatedund subsequently analyzed in cell culture. Using thisapproach, the neurogenic potential of embryonic radialglia cells was revealed. In addition, acutely isolatedtissue slices isolated from brain regions such as thebrain stem or hippocampus served for the analysisof the dynamic interaction of astroglial processeswith neighboring active synaptic terminals. Time-lapserecordings demonstrated highly motile lameUipodiaand filopodia emanating from major process branches.This work strengthened the view of astrocytes as regu-lators of neuronal transmission. However, astrocytesdo not just modulate neuronal function. In vivo, thepivotal role of astroglial endfeet associated with neigh-boring capillaries could be demonstrated. Transgenic labeling with the human GFAP pro-moter has been very helpful in identifying cells withastroglial properties in other species such as thezebra fish. Another important approach to labelastrocytes uses viral infections. Baculo-, lenti-,adeno-, and adeno-associated viruses carrying GFAPpromoter elements have been used to deliver genes ofinterest into astrocytes. Depending on brain regionand tropism of the viral substrain, even preferentialinfection of astrocytes can be achieved.
《神经科学百科全书》由科学出版社出版。
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书很专业，值得一看
书还可以啦，就是希望能是彩印版的更好。不过这个价格还是很划算的。
国内不可能买到这么好的书了